Anti-resorptive Cellular Activity Sampler

$699.00

Catalogue number: BV315102

This sampler kit includes two probes: 5-FAM-ZOL and AF647-ZOL. 5-FAM-ZOL has in vivo antiresorptive activity and can inhibit protein prenylation of macrophages; and AF647-ZOL has been shown inactive in these studies. This kit is ideal for studies that require imaging probes with and without pharmacological activity.

Kit Content:

  • 24 nmol of 5-FAM-ZOL
  • 24 nmol of AF647-ZOL
  • 10 mg of zoledronate (optional)
Please contact us for more details about the sampler kit: inquiry@biovinc.com

 

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Description

This sampler kit includes two probes: 5-FAM-ZOL and AF647-ZOL. 5-FAM-ZOL has in vivo antiresorptive activity and can inhibit protein prenylation of macrophages. AF647-ZOL has been shown inactive in these studies. This kit is ideal for studies that require imaging probes with and without pharmacological activity.

 

Spectroscopic properties of 5-FAM-ZOL:
Maximum absorption wavelength (λmax (abs)): 493 nm
Maximum emission wavelength (λmax (em)): 521 nm
Extinction coefficient (M-1cm-1):  73,000 (0.1 M phosphate buffer, pH 7.2)

 

Spectroscopic properties of AF647-ZOL:
Maximum absorption wavelength (λmax (abs)): 648 nm
Maximum emission wavelength (λmax (em)): 666 nm
Extinction coefficient (M-1cm-1):  240,000 (0.1 M phosphate buffer, pH 7.0)

 

*For laboratory use only. These products are intended for animal research only and not for use in humans.