BioVinc offers a complete line of Novel Fluorescent Bisphosphonate imaging probes to study bone metabolism. See our extensive catalog of high-quality commercialized research products. Note the wide variety of wavelengths, bone affinity and even pharmacological activity of these research reagents.

“The right tool to enhance your bone disease research.”

Three-Probe Bone Affinity Sampler

Name: Three-Probe Bone Affinity Sampler
SKU: BV355013
Price: 1199.0 USD
Availability: InStock

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SKU BV355013

$1,199.00

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Product Details

This sampler kit includes three imaging probes with different spectroscopic properties and high, medium and low bone affinities (in the order of 5(6)-ROX-RIS > 5(6)-FAM-dRIS > AF647-RISPC). All three probes include bisphosphonate or phosphonocarboxylate molecular skeleton, thus have higher affinity than calcein (the fluorescent molecule with the least bone affinity). The kit can be used for simultaneous detection with co-dosing and studies on effects of bone affinity.

Spectroscopic properties of 5(6)-ROX-RIS:

Maximum absorption wavelength (λmax (abs)): 580 nm

Maximum emission wavelength (λmax (em)): 605 nm

Extinction coefficient (M^-1cm^-1): 73,000 (0.1 M phosphate buffer, pH 8.0)

Spectroscopic properties of 5(6)-FAM-dRIS:

Maximum absorption wavelength (λmax (abs)): 493 nm

Maximum emission wavelength (λmax (em)): 518 nm

Extinction coefficient (M^-1cm^-1): 73,000 (0.1 M phosphate buffer, pH 7.2)

Spectroscopic properties of AF647-RISPC:

Maximum absorption wavelength (λmax (abs)): 648 nm

Maximum emission wavelength (λmax (em)): 666 nm

Extinction coefficient (M^-1cm^-1): 240,000 (0.1 M phosphate buffer, pH 7.0)

*For laboratory use only. These products are intended for animal research only and not for use in humans.

Three-Probe Bone Affinity Sampler

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