BioVinc offers a complete line of Novel Fluorescent Bisphosphonate imaging probes to study bone metabolism. See our extensive catalog of high-quality commercialized research products. Note the wide variety of wavelengths, bone affinity and even pharmacological activity of these research reagents.

“The right tool to enhance your bone disease research.”

Two-Probe Bone Affinity Sampler

Name: Two-Probe Bone Affinity Sampler
SKU: BV345012
Price: 899.0 USD
Availability: InStock

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SKU BV345012

$899.00

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Product Details

This sampler kit includes two imaging probes with different spectroscopic properties as well as variable bone affinities (AF647-RIS has stronger affinity than 5(6)-FAM-RISPC). The probes are fluorescent conjugates of risedronate, a widely used bisphosphonate drug in clinical applications, and its phosphonocarboxylate analogue. There is also an option of adding the calcein (a fluorescent molecule with even lower bone affinity) in the kit. The kit can be used for simultaneous detection with co-dosing and studies on effects of bone affinity, and is a great, economical complement to the 3-probe bone affinity kit.

Spectroscopic properties of AF647-RIS:

Maximum absorption wavelength (λmax (abs)): 648 nm

Maximum emission wavelength (λmax (em)): 666 nm

Extinction coefficient (M^-1cm^-1): 240,000 (0.1 M phosphate buffer, pH 7.0)

Spectroscopic properties of 5(6)-FAM-RISPC:

Maximum absorption wavelength (λmax (abs)): 493 nm

Maximum emission wavelength (λmax (em)): 518 nm

Extinction coefficient (M^-1cm^-1): 73,000 (0.1 M phosphate buffer, pH 7.2)

*For laboratory use only. These products are intended for animal research only and not for use in humans.

Two-Probe Bone Affinity Sampler

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