Showing all 6 results

anti-resorptive-cellular-activity-sampler-1-3
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Anti-resorptive Cellular Activity Sampler

$699.00

Catalogue number: BV315102

This sampler kit includes two probes: 5-FAM-ZOL and AF647-ZOL. 5-FAM-ZOL has in vivo antiresorptive activity and can inhibit protein prenylation of macrophages; and AF647-ZOL has been shown inactive in these studies. This kit is ideal for studies that require imaging probes with and without pharmacological activity.

Kit Content:

  • 24 nmol of 5-FAM-ZOL
  • 24 nmol of AF647-ZOL
  • 10 mg of zoledronate (optional)
Please contact us for more details about the sampler kit: inquiry@biovinc.com

 

confocal-imaging-sampler-1-2
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Confocal Imaging Sampler

$779.00

Catalogue number: BV325102

This sampler kit includes two imaging probes: the far red-fluorescent AF647-ZOL and near infrared fluorescent 800CW-ZOL. Both probes are fluorescent conjugates of zoledronate, a widely used bisphosphonate drug in clinical applications.  These bright and photostable imaging probes can be used for confocal microscopy imaging. Detection in the far red/near infrared optical window will minimize the interference from tissue autofluorescence.

Kit Contents:

  • 24 nmol of AF647-ZOL
  • 24 nmol of 800CW-ZOL
  • 10 mg of zoledronate (optional)
Please contact us for more details about the sampler kit: inquiry@biovinc.com

 

in-vivo-imaging-sampler-1-2
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In vivo Imaging Sampler

$749.00

Catalogue number : BV335012

This sampler kit includes two imaging probes: AF647-RIS and AF647-RISPC. The two probes have different bone mineral binding affinities but the same spectroscopic properties. AF647-RIS has stronger bone affinity than AF647-RISPC, thus a shorter circulatory half-life. In contrast, AF647-RISPC has fair bone affinity and a longer circulatory half-life. This sampler kit can be used for in vivo imaging studies.

Kit Contents:

  • 24 nmol of AF647-RIS
  • 24 nmol of AF647-RISPC
Please contact us for more details about the sampler kit: inquiry@biovinc.com

 

optical-imaging-sampler-1-2
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Optical Imaging Sampler

$579.00

Catalogue number: BV311012

This sampler kit includes two economical imaging probes: 5(6)-ROX-RIS and 5(6)-FAM-RIS. Both probes are fluorescen conjugates of risedronate, a widely used bisphosphonate drug in clinical applications. The probes have different spectroscopic properties and can be used for optical microscopy imaging.

Kit Content:

  • 24 nmol of 5(6)-FAM-RIS
  • 24 nmol of 5(6)-ROX-RIS
  • 10 mg of risedronate (optional)
Please contact us for more details about the sampler kit: inquiry@biovinc.com

 

three-probe-bone-affinity-sampler-1-2
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Three-Probe Bone Affinity Sampler

$999.00

Catalogue number: BV355013

This sampler kit includes three imaging probes with different spectroscopic properties and high, medium and low bone affinities (in the order of 5(6)-ROX-RIS > 5(6)-FAM-dRIS > AF647-RISPC). All three probes include bisphosphonate or phosphonocarboxylate molecular skeleton, thus have higher affinity than calcein (the fluorescent molecule with the least bone affinity). The kit can be used for simultaneous detection with co-dosing and studies on effects of bone affinity.

Kit Contents:

  • 24 nmol of 5(6)-ROX-RIS
  • 24 nmol of 5(6)-FAM-dRIS
  • 24 nmol of AF647-RISPC
Please contact us for more details about the sampler kit: inquiry@biovinc.com

 

two-probe-bone-affinity-sampler-1-2
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Two-Probe Bone Affinity Sampler

$749.00

Catalogue number: BV345012

This sampler kit includes two imaging probes with different spectroscopic properties as well as variable bone affinities (AF647-RIS has stronger affinity than 5(6)-FAM-RISPC). The probes are fluorescent conjugates of risedronate, a widely used bisphosphonate drug in clinical applications, and its phosphonocarboxylate analogue. There is also an option of adding the calcein (a fluorescent molecule even lower bone affinity) in the kit. The kit can be used for simultaneous detection with co-dosing and studies on effects of bone affinity, and is a great, economical complement to the 3-probe bone affinity kit.

Kit Contents:

  • 24 nmol of AF647-RIS
  • 24 nmol of 5(6)-FAM-RISPC
  • 10 mg of Calcein
Please contact us for more details about the sampler kit: inquiry@biovinc.com